A Synchronous Occurrence of Serous and Mucinous Cystadenomas of the Ovaries: Case Report and Review of the Literature.
Ovarian neoplasms are common gynecological tumors, with epithelial tumors accounting for the majority of cases. While serous and mucinous cystadenomas are frequent individually, the synchronous occurrence of different epithelial subtypes in bilateral ovaries is extremely rare.
We report a 55-year-old postmenopausal woman presenting with lower abdominal pain, swelling, nausea, vomiting, and unintentional weight loss. Imaging revealed a large multiloculated cystic pelvic mass. Serum CA-125 was normal. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathology demonstrated a left ovarian mucinous cystadenoma and a right ovarian serous cystadenoma. The uterus, cervix, and fallopian tubes were unremarkable. The patient recovered well postoperatively and remains on regular follow-up.
The simultaneous presence of distinct epithelial ovarian tumors in bilateral ovaries is rare, with limited reports in the literature. Preoperative imaging may suggest unilateral involvement, potentially masking the coexistence of multiple histologies. Intraoperative frozen section analysis, when available, can guide surgical decision-making and potentially prevent unnecessary removal of additional structures.
Clinicians should consider the possibility of synchronous ovarian epithelial tumors in differential diagnoses of ovarian masses. Accurate diagnosis relies on thorough clinical evaluation, imaging, and histopathological correlation. Surgical management followed by careful follow-up is effective for benign synchronous ovarian tumors.
We report a 55-year-old postmenopausal woman presenting with lower abdominal pain, swelling, nausea, vomiting, and unintentional weight loss. Imaging revealed a large multiloculated cystic pelvic mass. Serum CA-125 was normal. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathology demonstrated a left ovarian mucinous cystadenoma and a right ovarian serous cystadenoma. The uterus, cervix, and fallopian tubes were unremarkable. The patient recovered well postoperatively and remains on regular follow-up.
The simultaneous presence of distinct epithelial ovarian tumors in bilateral ovaries is rare, with limited reports in the literature. Preoperative imaging may suggest unilateral involvement, potentially masking the coexistence of multiple histologies. Intraoperative frozen section analysis, when available, can guide surgical decision-making and potentially prevent unnecessary removal of additional structures.
Clinicians should consider the possibility of synchronous ovarian epithelial tumors in differential diagnoses of ovarian masses. Accurate diagnosis relies on thorough clinical evaluation, imaging, and histopathological correlation. Surgical management followed by careful follow-up is effective for benign synchronous ovarian tumors.
Authors
Mbabazi Mbabazi, Dushimiyimana Dushimiyimana, Ruzindana Ruzindana, Musana Musana, Getaneh Getaneh, Manirakiza Manirakiza
View on Pubmed