Abdominal obesity, dynapenia, and cardiometabolic risk in patients with chronic kidney disease.
Dynapenic abdominal obesity (AO) is a recognized risk factor for hospitalization, disability, and mortality.
To examine the association between AO, dynapenia, and their coexistence with cardiometabolic risk factors in non-dialysis patients with chronic kidney disease.
A cross-sectional study was conducted with 91 patients at a nutrition and nephrology outpatient clinic in Bahia, Brazil. Adult and elderly individuals were classified into four groups based on handgrip strength and waist circumference: 1) non-AO/non-dynapenic (NAO/ND), 2) non-AO/dynapenic (AOD) (NAO/D), 3) AO/ND, and 4) AOD. Cardiometabolic risk was assessed via demographic, clinical, lifestyle, anthropometric, and biochemical parameters. Kruskal-Wallis, ANOVA, Chi-square tests, and Poisson regression were used for analysis.
The prevalence of AO/ND, NAO/D, and AOD was 58.2%, 38.5%, and 18.7%, respectively. In adjusted models, AO/ND was associated with increased body mass index (prevalence ratios [PR]: 1.15; 95% confidence intervals [CI]: 1.04-1.27). NAO/D was associated with hyperphosphatemia (PR: 1.77; 95% CI: 1.06-2.94). AOD was associated with diabetes mellitus (PR: 4.7; 95% CI: 1.44-15.7) and smoking (PR: 5.7; 95% CI: 1.26-25.5).
AO, dynapenia, and their coexistence were significantly associated with cardiometabolic risk factors in patients with early-stage chronic kidney disease, underscoring the importance of regular adiposity and muscle strength assessment in clinical practice.
To examine the association between AO, dynapenia, and their coexistence with cardiometabolic risk factors in non-dialysis patients with chronic kidney disease.
A cross-sectional study was conducted with 91 patients at a nutrition and nephrology outpatient clinic in Bahia, Brazil. Adult and elderly individuals were classified into four groups based on handgrip strength and waist circumference: 1) non-AO/non-dynapenic (NAO/ND), 2) non-AO/dynapenic (AOD) (NAO/D), 3) AO/ND, and 4) AOD. Cardiometabolic risk was assessed via demographic, clinical, lifestyle, anthropometric, and biochemical parameters. Kruskal-Wallis, ANOVA, Chi-square tests, and Poisson regression were used for analysis.
The prevalence of AO/ND, NAO/D, and AOD was 58.2%, 38.5%, and 18.7%, respectively. In adjusted models, AO/ND was associated with increased body mass index (prevalence ratios [PR]: 1.15; 95% confidence intervals [CI]: 1.04-1.27). NAO/D was associated with hyperphosphatemia (PR: 1.77; 95% CI: 1.06-2.94). AOD was associated with diabetes mellitus (PR: 4.7; 95% CI: 1.44-15.7) and smoking (PR: 5.7; 95% CI: 1.26-25.5).
AO, dynapenia, and their coexistence were significantly associated with cardiometabolic risk factors in patients with early-stage chronic kidney disease, underscoring the importance of regular adiposity and muscle strength assessment in clinical practice.
Authors
Almeida-Menezes Almeida-Menezes, Conceição-Machado Conceição-Machado, Gusmão Gusmão, Ramos Ramos, Barreto-Medeiros Barreto-Medeiros
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