Association between obesity and the intersection of depression, sex, and race in Brazilian adults: a cross-sectional analysis of population-based survey.

A bidirectional relationship between obesity and depression is reported; racial and sex inequities may contribute to this relationship in low- and middle-income countries.

Cross-sectional study with data from 2019 Pesquisa Nacional de Saude (Brazilian National Health Survey), aiming to investigate the association of obesity and the intersection between depression, sex, and race/skin color in Brazilian adults (n = 87,497). Depression was investigated using the Patient Health Questionnaire-9 and obesity by the Body Mass Index (BMI ≥ 30 kg/m²). Sex and race/skin color were analyzed separately and combined: white men; white women; black men; black women. Odds Ratios (OR) were estimated using Logistic regression models adjusted by sociodemographic data. Obesity was the outcome, while depression and its intersections with sex and race/skin color were explanatory variables. Individuals without depression were the reference group in all models.

Depression prevalence was 10.8%, and obesity prevalence was 21.3%. Depression was associated with a higher chance of presenting obesity in the total population (OR:1.37; p < 0.001). Women with depression had higher chance to present obesity (OR:1.55; p < 0.001) compared to those without depression. Black individuals with depression (OR:1.37; p < 0.001) and white individuals with depression (OR:1.38; p < 0.001) had similar higher chances to present obesity. Considering the intersection between sex and race/skin color, compared to individuals without depression, black women with depression presented 59% higher chance of obesity (OR:1.59; p < 0.001), followed by white women with depression (OR:1.50; p < 0.001).

Depression was associated with an increased chance of obesity with this relationship varying by sex and race/skin color. The strongest association was observed among black women.
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Authors

Caldeira Caldeira, Canella Canella, Rosa Rosa, Ramos Ramos, da Silva da Silva, Claro Claro, de Sousa de Sousa
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