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Yoga, an ancient discipline originating in India, primarily considered a spiritual practice, has now evolved into a recognized therapeutic modality addressing various health conditions, including chronic diseases, mental health disorders, and stress-related ailments. Despite its proven benefits and growing evidence base, the integration of yoga therapy into mainstream healthcare in India faces significant barriers. Key challenges include the perception of yoga as a spiritual or wellness practice rather than a clinical treatment, cost concerns limiting access for lower-income populations, and a lack of standardization in training, certification, and therapeutic protocols. Facilitators, however, indicate promising opportunities for broader acceptance. These include increasing public interest, government initiatives by bodies like the Ministry of AYUSH, and a growing body of research validating yoga's therapeutic efficacy. Efforts to establish regulatory frameworks and standardized guidelines are gaining momentum, fostering the credibility and integration of yoga therapy into healthcare systems. This article explores these barriers and facilitators influencing the utilization of yoga therapy in India and proposes strategies to enhance its adoption. By addressing misconceptions, improving accessibility of yoga healthcare professionals, efforts for standardization and regularization of education, and increasing collaboration between yoga practitioners and medical professionals, yoga therapy has the potential to become a cornerstone of holistic healthcare in India.