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Myiasis is the infestation of living or necrotic tissues of humans and animals by dipteran larvae. It is endemic to tropical and subtropical regions of the Americas and Africa. It occurs most frequently in vulnerable populations, and it is associated with open wounds, poor hygiene, and predisposing medical conditions. The objective was to describe 2 clinical cases of cutaneous myiasis in humans confirmed in Mexico.

The first case occurred in a 77-year-old woman, and it was secondary to mild traumatic brain injury according to the World Health Organization (WHO) classification. The second in a 74-year-old man with advanced basal cell carcinoma on the right side of his face. In both cases, samples were sent to the State Public Health Laboratory (LESP) and the National Service for Agrifood Health, Safety and Quality (SENASICA), where the taxonomic diagnosis of Cochliomyia hominivorax was confirmed.

Myiasis is a preventable disease of epidemiological importance which was considered eradicated in Mexico since 1991. Early diagnosis and comprehensive medical-surgical treatment allow for a favorable evolution and prognosis, with the prevention of serious complications.