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Cerebral venous thrombosis is a condition that can lead to a cerebrovascular accident and is associated with thromboses in the cerebral sinuses. The clinical presentation is often similar to ischemic cerebral infarction and depends on the location of the thrombosis, but one of the most common symptoms is headache. Cerebral venous thrombosis in most cases is associated with risk factors for this condition, such as pregnancy, various types of coagulopathy, autoimmune diseases, infections, etc. The objective of this paper is to present a clinical case of a patient with thrombophilia who developed thrombosis of the left transverse sinus.