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This systematic review study method to investigate the effects of yoga therapy in oncological nursing care for children undergoing cancer treatment. Between 2009 and 2024, searches were conducted in Science Direct, Web of Science, PubMed, and Google Scholar databases using the keywords "pediatric oncology, cancer, child, adolescent, yoga, nursing care, stress, fatigue, sleep quality," yielding a total of 502 studies, 45 of which were classified as articles. Twelve of the reviewed articles met the inclusion criteria. In this systematic review, the question "What is the effectiveness of yoga therapy on stress, fatigue, and sleep quality in pediatric oncology care?" was addressed. The reviewed articles found that yoga therapy improved stress, fatigue, physical activity, psychological well-being, sleep quality, and pain levels in pediatric oncology. While reviewing the articles, the identities of the authors, the publishing journals, the research method, the country in which the study was conducted, the number of patients, the age range of the intervention, the type of intervention, and the parameters determined to be effective on yoga were all examined, and it was concluded that yoga can be used as an alternative nursing care for children with cancer.