Global, regional and national prevalence of mental disorders among women at childbearing age from 1992 to 2021.
To investigate the trends in prevalence of mental disorders - schizophrenia, depressive disorders, bipolar disorder, anxiety disorders, eating disorders, autism spectrum disorders, attention-deficit/hyperactivity disorder, conduct disorder, idiopathic developmental intellectual disability, and other mental disorders - among women of childbearing age at global, regional and national level from1992 to 2021, and further to examine the independent effects of age, period, and birth cohort on mental disorders.
Data were derived from the Global Burden of Disease Study (GBD) 2021. An age-period-cohort analysis was adopted to investigate the annual percentage change in prevalence rate overall (net drifts, % per year) and by age (local drifts, % per year), and age-, period-, and cohort-effect on the prevalence rate among participants between 1992 and 2021.
In 2021, the global prevalence cases of overall mental disorders in women at childbearing age were 343.22 million. Over the past three decades, the largest increase in case number was observed in low socio-demographic index (SDI) region (144.21%), while the most significant increase in age-standardized prevalence rate (ASPR) was identified in high SDI region (18.30%). The global net drift in prevalence rate of mental disorders among participants was estimated as -0.02 (95%CI: -0.04 to -0.00) annually. Moreover, prevalence trends were highly heterogeneous across all the global 204 countries/territories. Anxiety disorders and depression disorders were the top two contributors of overall prevalence of mental disorders, accounting for the largest proportion of total prevalence (66.2% in 1992 and 70.4% in 2021) among all types of mental disorders. For overall global population, an increasing age effect, V-shape pattern of period effect, and stable cohort effect were separately identified upon mental disorder burden. Notably, the V-shape period effect may reflect that positive mental health policy gains (pre-2016) were disrupted by COVID-19 pandemic.
The global burden of mental disorders among women at childbearing age remained high during 1992 and 2021, especially after the COVID-19 pandemic. Notably, anxiety disorders, and depressive disorders were more prevalent in this population. Disparities of mental disorders existed in regions, countries and sub-populations with different age. These findings imply that mental health issue has become a significant public health challenge worldwide. This study has important policy and population health implications, suggesting that country-specific and subpopulation-tailored intervention strategies should be implemented for the purpose to reduce the burden of mental disorders among women at childbearing age worldwide.
Data were derived from the Global Burden of Disease Study (GBD) 2021. An age-period-cohort analysis was adopted to investigate the annual percentage change in prevalence rate overall (net drifts, % per year) and by age (local drifts, % per year), and age-, period-, and cohort-effect on the prevalence rate among participants between 1992 and 2021.
In 2021, the global prevalence cases of overall mental disorders in women at childbearing age were 343.22 million. Over the past three decades, the largest increase in case number was observed in low socio-demographic index (SDI) region (144.21%), while the most significant increase in age-standardized prevalence rate (ASPR) was identified in high SDI region (18.30%). The global net drift in prevalence rate of mental disorders among participants was estimated as -0.02 (95%CI: -0.04 to -0.00) annually. Moreover, prevalence trends were highly heterogeneous across all the global 204 countries/territories. Anxiety disorders and depression disorders were the top two contributors of overall prevalence of mental disorders, accounting for the largest proportion of total prevalence (66.2% in 1992 and 70.4% in 2021) among all types of mental disorders. For overall global population, an increasing age effect, V-shape pattern of period effect, and stable cohort effect were separately identified upon mental disorder burden. Notably, the V-shape period effect may reflect that positive mental health policy gains (pre-2016) were disrupted by COVID-19 pandemic.
The global burden of mental disorders among women at childbearing age remained high during 1992 and 2021, especially after the COVID-19 pandemic. Notably, anxiety disorders, and depressive disorders were more prevalent in this population. Disparities of mental disorders existed in regions, countries and sub-populations with different age. These findings imply that mental health issue has become a significant public health challenge worldwide. This study has important policy and population health implications, suggesting that country-specific and subpopulation-tailored intervention strategies should be implemented for the purpose to reduce the burden of mental disorders among women at childbearing age worldwide.