[Infrared thermography outcomes in women with suspected breast cancer].
Breast cancer (BC) is the most common cause of death in women aged 40 to 75 years. Infrared thermography (IT) has been proposed as a noninvasive test useful in the detection of BC.
To analyze the results of IT in women with suspected BC.
An analytical, observational, longitudinal, and prospective study was conducted. Women aged ≥ 15 years with suspected BC were included, with BI-RADS (Breast Imaging Reporting and Data System) 4. Prior to the biopsy, breast temperature was measured using 2 thermographic sensors. The histopathological results of the breast biopsy were recorded and classified as inflammatory lesions, fibrocystic breast disease, premalignant lesions, and malignant lesions.
A total of 104 women were analyzed, with BI-RADS 4A (64%), 4B (26%), and 4C (10%), and 4 were eliminated due to loss to follow-up. Mean age was 47.7 ± 12.2 years. 14% of cases showed a palpable lesion, with the right breast being the most affected (56%). The most common malignant lesion was ductal carcinoma (11%). The IT cutoff point for malignant lesion ≥ 33.4 °C showed a sensitivity of 0.69, specificity of 0.63, area under the curve (AUC) = 0.65 (95% confidence intervals [95% CI] 0.45-0.79), p = 0.03; with an odds ratio (OR) = 4.16 (95% CI 1.23-14.09), p = 0.01.
The results of the IT showed moderate sensitivity and specificity for malignant lesions. The cutoff point ≥ 33.4 °C showed a 4-fold increased risk for malignancy.
To analyze the results of IT in women with suspected BC.
An analytical, observational, longitudinal, and prospective study was conducted. Women aged ≥ 15 years with suspected BC were included, with BI-RADS (Breast Imaging Reporting and Data System) 4. Prior to the biopsy, breast temperature was measured using 2 thermographic sensors. The histopathological results of the breast biopsy were recorded and classified as inflammatory lesions, fibrocystic breast disease, premalignant lesions, and malignant lesions.
A total of 104 women were analyzed, with BI-RADS 4A (64%), 4B (26%), and 4C (10%), and 4 were eliminated due to loss to follow-up. Mean age was 47.7 ± 12.2 years. 14% of cases showed a palpable lesion, with the right breast being the most affected (56%). The most common malignant lesion was ductal carcinoma (11%). The IT cutoff point for malignant lesion ≥ 33.4 °C showed a sensitivity of 0.69, specificity of 0.63, area under the curve (AUC) = 0.65 (95% confidence intervals [95% CI] 0.45-0.79), p = 0.03; with an odds ratio (OR) = 4.16 (95% CI 1.23-14.09), p = 0.01.
The results of the IT showed moderate sensitivity and specificity for malignant lesions. The cutoff point ≥ 33.4 °C showed a 4-fold increased risk for malignancy.
Authors
Luna-Patiño Luna-Patiño, Sosa-Bustamante Sosa-Bustamante, Ibarra-Morán Ibarra-Morán, Gallegos-Ríos Gallegos-Ríos, León-Zamudio León-Zamudio, Luna-Anguiano Luna-Anguiano, Paque-Bautista Paque-Bautista, González González
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