Opioids and Respiratory Related Consequences.
Opioids are widely used in acute and chronic pain management, but have significant respiratory effects that pose risks, especially in hospital settings. Opioid-induced respiratory depression occurs with opioids suppress the body's respiratory rate and response to CO2, leading to life-threatening gas exchange impairment. Chronic use of opioids causes central sleep apnea with an irregular breathing pattern, and contributes to complexity in managing obstructive sleep apnea. Mitigating respiratory risks of opioids involves limiting doses, careful monitoring, and sometimes the use of respiratory support like non-invasive ventilation.