Patient-centric approaches and personalized nanomedicine in skin cancer.
One of the most common cancers in the world is still skin cancer, which includes both melanoma and non-melanoma forms like squamous cell carcinoma and basal cell carcinoma. Non-specificity, drug resistance, recurrence, and patient response variability are some of the drawbacks of traditional treatment modalities. In order to overcome these obstacles and improve the treatment of skin cancer, this review investigates the combination of personalized nanomedicine and patient-centric care models. Patient-centric approaches place a high value on shared decision-making, customized treatment plans, and ongoing feedback via mobile health technologies and patient-reported outcome measures (PROMs). At the same time, personalized nanomedicine uses sophisticated nanocarriers like liposomes, dendrimers, and gold nanoparticles to deliver targeted, effective, and less toxic therapies by utilizing molecular profiling and biomarker-guided strategies. When these paradigms are applied in concert, precise drug delivery is made possible, therapeutic results are improved, and treatments are tailored to the biological and psychosocial characteristics of the patients. The potential for these integrative approaches to revolutionize standard care in dermatologic oncology is highlighted in this paper along with their recent developments, clinical uses, and potential future directions.