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Childhood obesity represents one of the most significant public health and educational challenges of the modern era. The prevalence of overweight and obesity among children and adolescents has risen substantially worldwide over recent decades, affecting a large number of young people. In the United Kingdom, childhood obesity remains highly prevalent and is disproportionately concentrated in socioeconomically deprived communities. While cardiometabolic and psychosocial consequences are well established, evidence is accumulating that obesity also compromises neurocognitive development and academic achievement. This link has major implications for lifelong well-being and social mobility. This review was conducted to systematically evaluate contemporary evidence (2015-2025) exploring the relationship between childhood overweight or obesity and academic outcomes, including test performance, grades, attendance, and cognitive function, and to synthesize mechanistic explanations across biological, psychological, and social domains. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, PubMed, Web of Science, and Scopus were searched for English-language studies from January 2015 to July 2025. Eligible designs included cross-sectional, longitudinal, and interventional studies that measured overweight or obesity via BMI or equivalent anthropometric indices and reported at least one academic or cognitive outcome. Study quality was assessed using the Newcastle-Ottawa Scale (NOS) for observational studies and the Cochrane RoB 2.0 tool for randomized trials. Twenty studies (seven cross-sectional, ten longitudinal, and three interventional) met the inclusion criteria. Across diverse contexts, elevated BMI was consistently associated with poorer academic performance. Longitudinal analyses confirmed directionality: persistent overweight predicted slower progress in literacy and numeracy, independent of parental education or socioeconomic status (SES). Proposed mediators included inflammatory neuromodulation, sleep disturbance, stigma, and deprivation. School-based interventions integrating physical activity, nutrition education, and psychosocial support improved engagement and executive function despite modest BMI change. A modest but consistent inverse association exists between childhood obesity and academic achievement. The relationship is multidimensional, reflecting interactions between biology, behavior, and social context, and highlights the need for school-centered, equity-focused prevention strategies. Addressing obesity as both a health and educational issue could yield dual benefits in cognitive development and long-term well-being.