This review addresses the nutritional composition, health benefits, and claim conditions of aquaculture fish, focusing on gilthead sea bream (Sparus aurata) and European sea bass (Dicentrarchus labrax). Both species provide high-quality proteins, essential amino acids, and favorable lipid profiles, particularly long-chain omega-3 fatty acids, alongside minerals such as phosphorus and selenium, which meet EU criteria for several authorized nutrition and health claims. Evidence demonstrates that regular consumption supports cardiovascular, cognitive, and visual health, reduces inflammation, and contributes to better pregnancy and early childhood outcomes. Consumer skepticism toward aquaculture persists, often driven by perceptions of reduced nutritional quality, despite evidence that farmed fish provide nutritionally valuable proteins and beneficial lipids. Nevertheless, both species consistently meet the requirements for multiple nutrition and health claims, particularly those related to protein, omega-3 fatty acids, and selected minerals, allowing their effective use in labeling and consumer communication. Clear, evidence-based labeling of such claims is crucial to enhance acceptance and promote farmed fish as safe, sustainable, and health-promoting dietary choices.

Vision impairment is increasingly recognised as a complex condition shaped not only by ocular pathology but also by cognitive, psychological, social and environmental factors that influence participation and quality of life. In line with the United Nations Convention on the Rights of Persons with Disabilities and the International Classification of Functioning, Disability and Health, contemporary vision rehabilitation frameworks adopt a biopsychosocial perspective that extends beyond treatment of the eye condition alone toward holistic support to improve the lives of individuals with vision loss. An overview of the effectiveness and future directions of multidisciplinary vision rehabilitation in clinical practice is presented, and a summary of the findings concerning the international standards of vision rehabilitation, focusing on adults. Furthermore, some examples of achievements in emerging fields are presented, such as neuroplasticity and visual system recovery, technological interventions and psychosocial support, including their future directions. Multidisciplinary models are widely supported but remain difficult to implement because of limited resources, workforce constraints and differences in culture and health policy. Overcoming these barriers is critical to expanding and strengthening multidisciplinary vision rehabilitation. The evidence highlights the need for implementation-focused research, closer collaboration across disciplines and core outcome measures that capture participation, mental health and quality of life, not just impairment. The overview also points to the importance of structured models that integrate neurorehabilitation (artificial intelligence-based) technology and mental healthcare while adapting to regional and cultural contexts. Embedding multidisciplinary vision rehabilitation within health systems is both a clinical necessity and a prerequisite for advancing global commitments to inclusion and equity for people with vision impairment. As population ageing and global demographic change are expected to increase the absolute numbers of adults with vision loss, strengthening collaboration between research, clinical practice and service delivery will be essential to further improve the quality of life of individuals with vision loss.

The transition to fatherhood constitutes a substantial life event that can profoundly impact individuals and their relationships. This influence may be amplified when an anorexia nervosa (AN) is present within the family. This study aimed to examine paternal experiences during the pre- and postpartum period and assess how maternal AN influences these experiences.

Six semi-structured qualitative interviews were conducted with three male partners of women with and without AN, to explore their prepartum perspectives on the paternal role, their postpartum eating behaviors, overall well-being, and the impact of the AN on their relationship. The data was analyzed in accordance with the principles of qualitative content analysis as proposed by Mayring.

The analysis yielded six main categories that were deductively identified from the interview guide, with several sub-categories generated from the interview data. Many topics were raised by both groups and are in support of previous research. Group-specific aspects also emerged, such as a lower level of reflection on fatherhood among partners of women with AN. All partners of women with AN noted that the disorder affected the relationship, for example by causing conflicts.

The partly distinct experiences reported by the two groups highlight the impact of maternal AN on family dynamics and emphasize the need to incorporate paternal perspectives in eating disorder research during the transition to parenthood. Integrating fathers' experiences can enhance understanding of familial dynamics and inform the development of targeted interventions to support all family members during this critical period.

Evidence obtained from well-designed cohort or case-control analytic studies.

BackgroundAlzheimer's disease (AD) among patients with metabolic syndrome-related conditions is a global threat, contributing significantly to escalating mortality and economic burden. They demonstrate analogous pathophysiologies and risk determinants, highlighting the necessity for addressing this critical issue.ObjectiveThis study analyzed demographic trends and disparities of AD with metabolic syndrome-related conditions among patients aged 75 and above from 1999 to 2020.MethodsThis study examined the death certificates sourced from the CDC-WONDER database from 1999 to 2020, to analyze age-adjusted mortality rates (AAMRs) per 100,000 population. The Joinpoint regression model was used to assess trends in overall demographics, geographic, and place-of-death variables.ResultsThere were 2,355,233 deaths documented with AD listed as the underlying cause of death among older adults (aged ≥75), out of which 444,488 deaths were related to metabolic syndrome-related conditions from 1999 to 2020. The AAMR rose substantially from 36.48 in 1999 to 157.93 in 2020. Women consistently had higher AAMRs than males (females: 107.79, males: 79.02). Non-Hispanic African Americans (121.65) showed the highest mortality rates among all racial groups. However, from 1999 to the early to mid-2000s, all races highlighted a sharp peak in mortality rates. Striking geographical disparities were noted, with Mississippi in the top 90^th percentile and Massachusetts in the lower 10^th percentile.ConclusionsThis study reveals the demographic and geographic variations in mortality rates, highlighting the modalities of interventions and the need for equitable healthcare access.

Conditioned pain modulation (CPM) is a set of psychophysical paradigms that is increasingly used clinically to evaluate descending pain modulation pathways. Impairment is common in chronic pain, suggesting CPM may serve as a mechanistic indicator. However, the lack of protocol standardization and reference data prevents clinical use in individual patients.

We compared two CPM protocols with different conditioning stimulus intensities, test stimulus types, and interaction timing. We assessed CPM effect size, test-retest reliability and sensitivity to detect loss of descending inhibition.

Conditioning with 0°C water led to stronger inhibition of pressure pain threshold (PPT) than conditioning with 7°C water (Cohen's d = 0.52), when tested immediately after conditioning. When tested during conditioning, effects of 7°C water immersion on heat pain sensitivity had similar magnitude (D = 0.53) and test-retest reliability (ICC = 0.77) as those on PPT (D = 0.54, ICC = 0.73). For all outcomes assessed, 95% confidence intervals (CI) of CPM effect included some facilitation instead of inhibition. The maximum degree of facilitation compatible with normal CPM (upper cutoff of CI) indicates potential sensitivity to detect individual abnormality. This was most favourable for PPT assessed after conditioning with 0°C water (decrease by more than 75 kPa or 14% of baseline PPT).

In conclusion, testing during conditioning stimulation yields medium to large effect sizes and good test-retest reliability. PPT testing immediately after ice water immersion has the narrowest 95% CI and hence offers the potential to generalize CPM assessments beyond group-level differences and compare inhibition among individuals in clinical practice.

Indicating the main aspects where this work adds significantly to existing knowledge in the field, and if appropriate to clinical practice. Simultaneous CPM protocols exhibit large effect sizes but are confounded by divided attention. We recommend a sequential protocol and provide model reference data for abnormal facilitation.

The rising incidence of adolescent depression in China causes significant impairments, necessitating rapid treatments such as accelerated Intermittent theta-burst stimulation (iTBS). However, responses to treatment vary. We used naturalistic functional magnetic resonance imaging (N-fMRI) to investigate the impact of depression on the neural processing of emotional arousal. The objectives of this study were: 1) to identify brain regions associated with treatment response, and 2) to correlate these neural signatures with clinical outcomes following accelerated iTBS.Fifty-eight adolescents with depression and twenty-nine healthy controls underwent fMRI while viewing emotion-evoking videos. Forty-three patients completed accelerated iTBS treatment, with pre- and post-treatment fMRI scans. Statistical analysis of the MRI data was performed in SPM12, employing cluster-based family-wise error correction at a significance threshold of p < 0.05.Whole-brain analysis revealed that adolescents with depression exhibited significantly reduced emotion-arousal activation in the left superior frontal gyrus (L-SFG) and left middle frontal gyrus (L-MFG) compared to healthy controls during high-to-medium emotional arousal. Hamilton Depression Scale scores significantly decreased after iTBS treatment. L-MFG showed a marginally significant increase in emotion-arousal activation after iTBS. Correlation analysis between the Euclidean distance of treatment targets to the L-SFG and psychological scale scores revealed a significant negative association between the Euclidean distance and Generalized Anxiety Disorder-7 reduction rate.This exploratory study suggests that abnormal activity in the L-SFG and L-MFG underlies the variable efficacy of accelerated iTBS in adolescent depression. Our findings indicate that in an exploratory analysis, proximity to the L-SFG is correlated with treatment response, and L-MFG beta values showed slightly increased post-treatment. These preliminary results highlight these regions as potential neuroanatomical targets for future confirmatory research as biomarkers for iTBS mechanisms.

Occupational burnout is common in the mental health care workforce, with negative consequences for professionals and patients. This study aimed to evaluate the efficacy of a digital health intervention to alleviate burnout in psychological therapists.

This randomized controlled trial recruited 135 therapists working across 17 psychological services in England. The intervention involved six online group webinars based on principles of job crafting. Half of the participants accessed the intervention immediately (Group 1), and half were assigned to a waitlist control group (Group 2). After 6 weeks, Group 2 started the intervention. Participants completed measures of burnout (primary outcome), well-being, and job satisfaction at four time points (baseline, 6, 12, 36 weeks). Outcomes were compared between groups using mixed-effects models controlling for baseline severity and clustering by service.

Differences between groups were statistically significant after 6 weeks, favoring job crafting versus waitlist control in burnout (d = 0.43, p < .001), well-being (d = -0.39, p = .023), and job satisfaction (d = -0.28, p = .006) measures. However, the magnitude of improvements relative to baseline levels declined over a 36-week period.

A brief job crafting intervention led to short-term improvements in occupational health indicators. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Exposure to maternal mental illness in the first 3 years of life is associated with poor child outcomes. Many mothers experience mental health problems and few have access to evidence-based treatments. Mobile health treatments show promise for mood and anxiety disorders but rarely include parenting strategies. This study evaluated the efficacy of Building Emotional Awareness and Mental Health (BEAM), a 10-week app-based therapist-guided program, which responds to maternal mental health and parenting needs.

A two-arm, Phase III randomized controlled trial was conducted to evaluate the BEAM intervention compared to unrestricted services-as-usual. Participants completed self-report measures at eligibility, prior to randomization, and immediately following the intervention. The sample included 140 mothers with children aged 18-36 months, who self-reported moderate-to-severe symptoms of depression and/or anxiety.

Participants in both groups experienced significant decreases in depression over time with no significant difference between groups. However, BEAM outperformed the unrestricted services-as-usual condition in reducing anxiety symptoms. Among participants with higher levels of anxiety and depression symptoms at screening, those assigned to BEAM experienced greater reductions in anxiety, anger, and dysfunctional parenting interactions as well as lower harsh parenting composite scores compared to unrestricted services-as-usual.

BEAM is a highly scalable intervention that has the potential to rapidly reach underserved groups in need of mental health and parenting support. Next steps include improving the user interface and exploring engagement and implementation of the program within existing health and social service systems for long-term improvements in family health and well-being. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Culturally adapted parent training prevention interventions are critical for supporting the mental health and resilience of Latine immigrant families. Following the onset of the COVID-19 pandemic, parent training programs transitioned to online delivery, increasing flexibility and expanding access. This qualitative study explored the experiences of first-generation Latine immigrant caregivers (N = 22) in central Texas-86.4% of whom were of Mexican origin-who participated in a culturally adapted, synchronous online parent training program during the pandemic. Most participants were mothers (21 of 22). Through thematic analysis of focus group data, four key themes were generated: (a) immigration-related experiences and parenting challenges, (b) intervention components that addressed these challenges, (c) barriers and facilitators to participation, and (d) ongoing parenting needs. Caregivers reported increased parenting confidence and skill acquisition, alongside a sense of validation and support through the online community. While the virtual format enhanced accessibility, some participants encountered technological barriers. Key facilitators included the cultural competence of interventionists and the creation of a safe space for sharing immigration experiences. Participants highlighted the needs for further adaptation, including more father engagement, adolescent-focused content, and support in addressing intergenerational parenting patterns. Findings underscore the importance of creating therapeutic spaces that acknowledge immigration-related trauma and stress while building parental resilience and family well-being. These findings provide valuable insights for improving online synchronous delivery formats to enhance accessibility while maintaining program effectiveness and cultural responsiveness, promoting mental health equity for immigrant communities. Clinical and empirical implications are discussed. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Using data from the EU-GEI Work Package 2 (EU-GEI WP2) programme, we sought to test several hypotheses related to gaps in our knowledge of associations between childhood adversities and psychosis.

EU-GEI WP2 comprises incidence and case-control studies of first-episode psychosis conducted in 17 sites in 6 countries. In each site, over 2-year periods, we identified and collected relevant data from individuals aged 18-64 with a first-episode psychosis and with no history of psychosis. Missing data were imputed. We used multi-level logistic regression to test our hypotheses.

In total, 1071 cases and 1497 controls were included. We found variations in the prevalence and the magnitude of associations between any adversity and psychosis by place (eg, odds ratios ranged from 0.4 [Cuenca, Spain] to 12.1 [Madrid, Spain]). The weighted percentages reporting adversities in control samples were associated with site incidence rates (eg, 3+ adversities: Spearman's rho 0.56, P .025). We found variations in the magnitude of associations by sex (eg, effect of physical and sexual abuse stronger among women), by age of exposure, and by severity and frequency of adversities (eg, largest odds ratios for adversities involving hostility, threat, and violence).

Variations across populations in prevalence and effects of adversities may contribute to variations in rates of psychosis. Variations in effects by sex and age of onset may point to sex-specific mechanisms and to developmentally sensitive periods. Adversities involving severe threat, hostility, and violence may have the largest effects on risk of psychosis.