Intraosseous schwannoma of the mandible is a rare benign nerve sheath tumor that often resembles an odontogenic lesion radiographically. As many reported cases are asymptomatic, the absence of neurosensory symptoms is not a specific diagnostic clue. We report a 33-year-old female with a mandibular lesion detected incidentally on panoramic radiography. She had no pain, swelling, or numbness, and neurosensory examination of the mental nerve distribution was normal. The involved teeth were vital and showed no mobility or percussion pain. Panoramic radiography revealed a well-defined unilocular radiolucency extending from the right mandibular premolar region to the mesial root of the first molar. Computed tomography showed a relatively homogeneous low-attenuation lesion, inferior displacement of the mandibular canal, smooth thinning and resorption of the buccal and lingual cortices, and remodeling and enlargement of the mental foramen, without root resorption. Thus, marked remodeling centered on the inferior alveolar nerve pathway was present despite preserved neurosensory and pulpal function, demonstrating radiographic-clinical dissociation. Surgical excision revealed an encapsulated yellowish-brown solid mass adherent to the inferior alveolar nerve near the mental foramen; funnel-shaped enlargement of the mental foramen was observed intraoperatively. Histopathological examination demonstrated mixed Antoni A and Antoni B areas, and the tumor cells were positive for S100 protein and neuron-specific enolase, confirming schwannoma. Mild postoperative hypoesthesia resolved within five months, and no recurrence was observed during the available two-year follow-up. The combination of mandibular canal displacement and mental foramen enlargement may suggest a neurogenic origin and aid differential diagnosis and nerve-preserving surgical planning, even in patients without neurosensory symptoms.

Significant disparities in mental health service utilization persist, particularly among Black adults in the United States. We focused on ethnic identity dimensions of centrality and assimilation and addressed their distinction from the commonly used term of acculturation.

This study utilized gamma regression to examine the relationship between ethnic identity and help-seeking behavior within a large sample of Black adults (N = 1,117) and investigated the moderating effects of stigma-related barriers on this relationship.

The findings revealed statistically significant differences in centrality (extent to which a person identifies with their race), and assimilation (desire for integration into the mainstream parts of society) across gender, ethnicity, and age groups. Participants aged 45-65 scored higher in centrality compared to those aged 25-44. In terms of assimilation, males scored higher than females, and African/Afro-Caribbean immigrants scored higher than African Americans. Stigma-related barriers, including stigma within the workplace and concerns about being perceived as an unfit parent were notable deterrents to seeking mental health care. Centrality and assimilation were negatively associated with help-seeking intentions, such that higher levels of centrality and assimilation were related to lower intentions to seek mental health care for personal/emotional issues and suicidal thoughts. Stigma-related barriers moderated the relationship between education and help-seeking behavior. As stigma-related barriers increased, Black adults with higher education levels experienced a 17% decrease in help-seeking likelihood for personal/emotional issues (RR = 0.83, p < .01) but a 16% increase in help seeking for suicidal thoughts (RR = 1.16, p < .05).

These findings highlight the moderating effect of stigma-related barriers in relationships between ethnic identity dimensions and mental health service utilization among Black adults, underscoring the need for targeted, culturally informed interventions.

Smokeless tobacco (SLT) is used not only for recreation, but also for traditional healing, spiritual practices, and medicinal purposes. Understanding the motivations and lived experiences underlying these diverse forms of use is important for developing culturally-appropriate tobacco control interventions. This study explored the drivers, mode of use, perceived harms and lived experiences associated with traditional and non-traditional SLT use among adults in KwaZulu-Natal, South Africa.

A qualitative phenomenological design was used. In-depth interviews were conducted with 25 adults who used SLT primarily for traditional purposes (traditional health practitioners [THPs] and trainees/initiates [n=12]) or non-traditional purposes (n=13). Participants were recruited using convenience, purposive and snowball sampling. All interviews were audio-recorded, transcribed verbatim, translated where necessary, and analysed thematically using Braun and Clarke's six-phase framework aided by NVivo v12.

Four key themes emerged: motivations for SLT use, modes and practices of use, experienced harms, and perceptions of harmfulness. Traditional users described SLT use as part of ancestral communication, initiation into traditional healing, ritual practices, and traditional treatment. Non-traditional users reported using SLT for stress relief, perceived medicinal benefits, sexual enhancement, affordability compared with smoking, and social influence. Multiple modes of use were reported, including oral, nasal, intravaginal, and external ritual use. Participants described health-related, social, and financial harms associated with SLT use. However, some traditional users perceived SLT used within traditional healing contexts as protected from harm through ancestral or spiritual authority.

SLT use in KwaZulu-Natal is shaped by cultural, spiritual, medicinal, psychological, sexual, and economic motivations. Although participants reported multiple harms, cultural beliefs and perceptions of spiritual protection may influence risk perceptions and continued use. Public health interventions should address both the health risks of SLT and the cultural meanings attached to its use while engaging THPs and communities in developing culturally-acceptable prevention and cessation approaches.

With the expansion of theories concerning aging and the rapid evolution of artificial intelligence (AI) methodologies, the integration of AI and longevity medicine has emerged as a critical pathway for extending human healthspan. This study is aimed at a systematic characterization of the research landscape, collaboration networks, and frontier trends in this interdisciplinary field, so as to inform clinical translation and the development of the health management industry.

The Web of Science Core Collection, including Science Citation Index Expanded (SCIE) and Social Sciences Citation Index (SSCI), was used as the data source. English-language publications in the interdisciplinary field of AI and longevity medicine between 2010 and 2025 were systematically retrieved, and 4170 valid records were included for a joint analysis using Bibliometrix and CiteSpace 7.0.

Annual publication output showed exponential growth. The global research landscape exhibited a China-US dual-core and a multipolar pattern, with institutional collaborations clustering into 3 major networks spanning Asia-Europe, the United States, and Continental Europe. Research topics were clustered into five major themes-the core concepts of aging and multimorbidity, AI-driven body composition and musculoskeletal assessment, deep-learning-based evaluation of brain aging through neuroimaging, wearable sensing and mobile health, and digital phenotyping and mental health. Marked differences in research priorities were observed among the three leading contributors, including China, the United States, and the United Kingdom. China demonstrated broad research coverage and clinically oriented multi-track development, the United States led in methodological innovation and digital phenotyping, and the United Kingdom concentrated on brain age research.

This study systematically delineates the research landscape, collaboration networks, and frontier trajectories in the interdisciplinary field of AI and longevity medicine, providing data-driven evidence and decision-making support for advancing clinical translation and the development of the health management industry in this field.

Depression and anxiety symptoms among college students have become major public health concerns worldwide, including in China. In the context of increasing digitalization, college students are deeply engaged with online and mobile technologies, which may also exacerbate digital inequalities. The second digital divide, conceptualized in this study as disparities in internet literacy and internet attitudes after basic access to digital technologies has been achieved, has emerged as an important form of digital inequality among college students. Its potential triggers and underlying mechanisms linking it to mental health remain underexplored. Parental rearing styles are established consistently linked to factors for depression and anxiety, but whether they affect mental health through the digital divide is unknown. This study aimed to (1) identify distinct parental rearing profiles; (2) evaluate the impact of different parental rearing styles on mental health issues; (3) investigate whether the second digital divide mediates this association.

A cross-sectional study with a sample of 3533 college students was carried out. Latent profile analysis and multivariate logistic regression were conducted. Mediation analyses evaluated the mediating effects.

Three parental rearing style profiles were identified: positive, mixed, and negative parenting. Students with negative parental rearing style had the highest odds of depression, anxiety and their comorbidity, whereas those with mixed parental rearing styles also had higher odds than those with positive parental rearing styles. The second digital divide significantly mediated all associations. The subgroup and sensitivity analysis found that results remained unchanged.

Narrowing the second digital divide and promoting positive rearing styles may serve as a valuable direction for college students' mental health management.

South Africa's escalating mental health crisis, compounded by limited access to culturally responsive care, calls for innovative and contextually grounded interventions. While Large Language Models (LLMs) show considerable promise for mental health support, their predominantly Western-centric training data limit cultural and linguistic applicability in African contexts. This study introduces a proof-of-concept framework that integrates Cognitive Behavioural Therapy (CBT) with the African philosophy of Ubuntu to create a culturally sensitive, emotionally intelligent, AI-driven mental health dialogue system.

Guided by a Design Science Research (DSR) methodology, the framework applies both deep (theoretical and therapeutic) and surface-level (linguistic and communicative) cultural adaptations. Key CBT techniques, Behavioural Activation and Cognitive Restructuring, were reinterpreted through Ubuntu principles emphasizing communal well-being, spiritual grounding, and interconnectedness. A culturally adapted dataset was developed through iterative processes of language simplification, spiritual contextualization, and Ubuntu-based reframing. The fine-tuned model was evaluated through expert-informed case studies, employing UniEval for conversational quality assessment and additional measures of CBT reliability and cultural-linguistic alignment.

Results demonstrate that the model effectively engages in empathetic, context-aware dialogue aligned with both therapeutic and cultural objectives. Although real-time end-user testing has not yet been conducted, the model underwent rigorous review and supervision by domain-specialist clinical psychologists.

The findings highlight the potential of culturally embedded emotional intelligence in enhancing the contextual relevance, inclusivity, and effectiveness of AI-driven mental health interventions across African settings.

Mindfulness is increasingly used in global mental health, yet its measurement tools are largely developed within Western cultural frameworks. This study aimed to (1) translate and culturally adapt the Southampton Mindfulness Questionnaire (SMQ) into Khmer, (2) evaluate its cultural integrity among Cambodian adults with physical disabilities, and (3) examine the psychometric properties and factor structure of the measure.

The SMQ was translated using a standardised forward-backward translation process with expert panel review and cognitive interviewing. Exploratory (EFA) and Confirmatory Factor Analyses (CFA) were conducted on responses from 437 Cambodian participants with physical disabilities.

Following cultural adaptation, minor linguistic revisions were made to ensure conceptual equivalence. EFA and CFA supported a 14-item, six-factor structure comprising letting go, acceptance, non-judgement, cognitive-emotional reactivity, absence of aversion, and mindful observation. This structure demonstrated good model fit and internal consistency, diverging from the original Western single-factor model.

This study provides a culturally adapted Khmer version of the SMQ with evidence of structural validity and internal consistency and offers evidence that the structure of mindfulness may vary across cultural contexts. The findings highlight the influence of Buddhist psychological concepts, particularly acceptance and reduced cognitive-emotional reactivity, in shaping the experience of mindfulness in Cambodia. The availability of this scale enables culturally grounded research and clinical practice and supports the development of contextually appropriate mindfulness-based interventions in low- and middle-income settings.

Workplace violence is a significant occupational hazard in healthcare systems worldwide and may have serious psychological consequences for healthcare workers. Exposure to violence can contribute to the development of occupational burnout and post-traumatic stress disorder (PTSD), negatively affecting both staff well-being and the quality of healthcare services.

To analyze the types of workplace violence, associated risk factors, and the relationship between exposure to violence, occupational burnout, and post-traumatic stress disorder among healthcare workers.

A quantitative cross-sectional non-experimental study was conducted among 432 healthcare workers from Yerevan and the regions of Armenia. Workplace violence was assessed using the collaboratively developed and internationally validated questionnaire within ICREATE project. Burnout was evaluated using the Maslach Burnout Inventory, while PTSD symptoms were assessed using the DSM-5 PCL-5 questionnaire among participants who reported exposure to violence (n = 305). Statistical analyses included Chi-square tests, Cramer's V coefficient, independent samples t-tests, one-way ANOVA, and logistic regression.

Verbal violence was reported by 333 participants, physical violence by 184, sexual harassment by 77 and sexual violence by 10 healthcare workers. High or very high levels of occupational burnout were observed in the majority of respondents. Statistical analysis revealed significant associations between physical and verbal violence and higher levels of emotional exhaustion, depersonalization, and overall burnout (p < 0.05). Ordinal logistic regression analysis indicated that healthcare workers exposed to physical violence had approximately three times higher odds of experiencing higher levels of burnout (OR≈3.02; 95% CI: 1.98-4.63). Among participants exposed to violence, 64.9% reached the threshold score for probable PTSD. Physical violence was significantly associated with PTSD (χ² = 30.130, p = 0.000), and logistic regression analysis showed that exposure to physical violence increased the likelihood of PTSD by approximately 3.4 times.

Workplace violence is strongly associated with occupational burnout and PTSD among healthcare workers. Physical and verbal violence represent key predictors of adverse psychological outcomes.

Immigrants negotiate aspects of their heritage and host cultures to adapt to their new social environment through the acculturation process. This process influences health and well-being in immigrant communities. Arab American immigrants in the United States face unique cultural dynamics that shape their experiences, including healthcare experiences. This study addresses a gap in knowledge about culture as a social determinant of health awareness, healthcare access, and healthcare quality among Arab Americans. Guided by acculturation theory, we conducted thematic analysis of semi-structured interviews with 20 Arab Americans. Themes emerged revealing that culture, religion, and family function as both facilitators and barriers to healthcare. Cultural norms often promote self-care and healthy behaviors, but may discourage seeking medical treatment, particularly for mental health concerns. Religion was described as a flexible influence on healthcare decisions. Participants preferred providers of similar ethnic backgrounds due to perceived cultural understanding, and participant recommendations for providers highlighted the need for improved cultural competency training among healthcare professionals. Research on culturally responsive healthcare and training and policy solutions that enhance providers' cultural responsiveness are needed to improve healthcare experiences for Arab American patients and other immigrant populations.

Health-risk behaviors (HRBs) frequently co-occur during adolescence and are associated with adverse physical and mental health outcomes. This study aimed to identify latent classes of HRBs and examine the associations of psychological resilience (PR) and self-control (SC) with class membership.

In this cross-sectional study conducted in 2023, 11,407 students from 90 schools were recruited using multistage stratified cluster sampling. Latent class analysis (LCA) was used to identify patterns of HRBs. Chi-square tests and multinomial logistic regression were used to examine sociodemographic and psychological factors associated with class membership.

Four latent classes were identified: the Low-Risk Group (45.6%), the Physical Inactivity-Insufficient Sleep Group (21.8%), the Depressive Symptoms-Self-Harm-Picky Eating Group (26.3%), and the Multiple Health-Risk Behavior Group (6.4%). Relative to the Low-Risk Group, each one-point increase in psychological resilience was associated with a 3.4% reduction in the odds of membership in the Physical Inactivity-Insufficient Sleep Group (OR = 0.966, 95% CI: 0.957-0.976), a 6.6% reduction in the Depressive Symptoms-Self-Harm-Picky Eating Group (OR = 0.934, 95% CI: 0.925-0.942), and a 4.2% reduction in the Multiple Health-Risk Behavior Group (OR = 0.958, 95% CI: 0.945-0.972). Corresponding reductions in odds for self-control were 2.1% (OR = 0.979, 95% CI: 0.973-0.986), 6.2% (OR = 0.938, 95% CI: 0.932-0.943), and 8.8% (OR = 0.912, 95% CI: 0.903-0.921). Male gender was associated with significantly elevated odds of membership in the Multiple Health-Risk Behavior Group (OR = 2.275, 95% CI: 1.808-2.863), whereas rural residence was associated with lower odds of membership in the Physical Inactivity-Insufficient Sleep Group (OR = 0.530, 95% CI: 0.452-0.620) and the Depressive Symptoms-Self-Harm-Picky Eating Group (OR = 0.645, 95% CI: 0.565-0.737).

Chinese adolescents exhibited heterogeneous patterns of HRBs. Higher psychological resilience and self-control were independently associated with lower odds of membership in the three non-low-risk classes. These findings may inform class-specific prevention strategies.