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Community engagement as a foundation for implementation research for group psilocybin assisted therapy in New Mexico.3 weeks agoInformed by a community engagement process, we have developed a pragmatic, open-label, hybrid feasibility-implementation study of Group Psilocybin-Assisted Therapy (GPAT) for post-traumatic stress disorder (PTSD). As psychedelic-assisted therapies begin to enter the broader mental health arena, engaging communities in the design of research and care models is essential to ensuring that those most impacted have access to-and trust in-the treatments being developed. Guided by the principle of "nothing about us without us," the proposed study was designed from the outset to be community-informed and co-designed. We established a tripartite collaborative partnership among researchers from the University of New Mexico (UNM) Department of Family & Community Medicine (DFCM) and the UNM Office for Community Health (OCH), the Bernalillo County Health Equity Council, and the national Psychedelic Mental Health Access (PMHA) Alliance. The protocol for the FDA-approved study uses a group therapy model incorporating peer facilitators with shared affinity with the participant group. There will be six groups of six participants, including veterans/first responders and women survivors of sexual violence. The study is aligned with the New Mexico Therapeutic Psilocybin Program in its focus on access and equity, as well as the use of state-regulated whole psilocybin mushrooms rather than synthesized psilocybin. Each group will participate in two sessions using psilocybin mushroom-infused chocolates containing 20 mg and 30 mg of psilocybin, along with both group and individual therapy sessions. Outcomes will include safety and feasibility measures, as well as standard measures of PTSD, including the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Checklist for DSM-5 (PCL-5). An extended integration model provides longer-term support to participants both within and beyond the clinical trial. A barrier to scaling psychedelic-assisted therapy is understanding what it actually costs to deliver a safe, comprehensive model of care, particularly for populations facing structural barriers to access. The University of California, Berkeley Collaborative for the Economics of Psychedelics (CEP) will conduct a prospective micro-costing study in parallel with GPAT. The analysis will capture delivery costs for community engagement, the group psilocybin therapy model, and the post-clinical protocol extended integration program.
https://clinicaltrials.gov/study/NCT07506395.Mental HealthAccessCare/ManagementAdvocacy -
The intervention effect of caffeine oral tablets on mental fatigue induced by nap deprivation: based on assessments of heart rate variability, cognitive performance and subjective fatigue-a pilot study.3 weeks agoThis study aimed to investigate the feasibility of inducing mental fatigue (MF) through nap deprivation, based on monitoring heart rate variability (HRV), cognitive performance, and subjective fatigue levels. Additionally, the intervention effect of caffeine oral tablets (COT) on MF was evaluated.
This was an open-label, non-randomized, single-sequence crossover pilot study. The caffeine content in COT was quantified using high-performance liquid chromatography (HPLC). Ten healthy volunteers who habitually took naps were enrolled. Participants underwent nap deprivation to induce MF. Various parameters were collected at different time points, including the Karolinska Sleepiness Scale (KSS), Attention Network Task (ANT), and HRV metrics. Changes in each parameter before and after COT intervention were analyzed.
Following nap deprivation, there was a significant increase in KSS scores for the control group compared to baseline measurements taken after 2 h of sleep deprivation (P < 0.01). No significant changes were observed in ANT performance; however, HRV exhibited variations influenced by circadian rhythms-showing increased volatility in time-domain parameters and differing trends in frequency-domain parameters without statistical significance. After administration of low-dose COT to experimental participants, KSS scores did not significantly rise; conversely, correct response rates (CR) on ANT improved significantly (P < 0.05), alongside notable changes in both time-domain and frequency-domain HRV parameters (P < 0.05).
In this pilot study, the alignment between subjective and objective indices suggests that low-dose COT is associated with favorable changes in the MF state of volunteers following sleep deprivation. However, due to the small sample size and open-label design, these findings should be considered preliminary and warrant confirmation in larger, randomized controlled trials.Mental HealthAccessCare/ManagementAdvocacy -
The Impact of the COVID-19 Pandemic on Homecare Use for Individuals with Physical Disabilities Stratified by Sex, Age, and Mental Health Condition: A Cohort Study Using Administrative Health Data.3 weeks agoThis study investigated the impact of the COVID-19 pandemic on homecare service use among individuals with physical disabilities, stratified by age, sex, and mental health conditions.
Monthly utilization of personal support and nursing services was assessed using linked health administrative databases from ICES in Ontario, Canada, over two periods: pre-pandemic (March 2015 to February 2020) and during the pandemic (March 2020 to June 2022). Predictive Autoregressive Integrated Moving Average (ARIMA) models were used to estimate changes in service use.
During the pandemic, personal support service use declined significantly across multiple subgroups with some groups experiencing greater impacts. Significant decreases were observed in 78.5% of months for males, 14.3% for females, 78.5% for individuals aged 65 years and younger, 17.9% for those older than 65 years, and 78.5% for individuals with mental health conditions. In contrast, nursing service use increased significantly, with significant increases observed in 85.7% of months for males, 60.7% for females, 60.7% for those aged 65 years and younger, 17.9% for those older than 65 years, 85.7% for individuals with mental health conditions, and 28.6% for those without mental health conditions.
The findings highlight substantial variation in the pandemic's impact across subpopulations, with certain groups disproportionately affected. Targeted strategies are needed to mitigate these disparities and ensure equitable access to homecare services. Further research is warranted to explore the long-term implications and the underlying factors contributing to these differences.Mental HealthAccess -
Early Evidence of Geographic Variation in Medicare Participation Among Newly Eligible Mental Health Providers Following the 2024 Coverage Expansion.3 weeks agoTo assess changes in marriage and family therapist (MFT) and mental health counselor (MHC) workforce distribution from April 2022 to October 2024, evaluating early impacts of Medicare's coverage expansion on provider participation in underserved rural communities.
This repeat cross-sectional study used Medicare Fee-for-Service Public Provider Enrollment Files and National Provider Identifier Registry data. Counties were categorized as metropolitan and rural (micropolitan or noncore) using Urban Influence Codes. We analyzed quarterly changes in Medicare participation and the proportion of counties with at least one participating provider across geographic categories.
From April 2022 to October 2024, MFTs participating in Medicare increased from 111 to 9394, and MHCs increased from 4013 to 24013. Initially, participation rates were low and did not differ significantly by rurality. By October 2024, participation rates were higher in rural versus metropolitan counties for both provider types (MFTs: 16.4% rural vs. 11.0% metropolitan; MHCs: 12.1% vs. 9.2%; both p < 0.001). The percentage of counties with at least one Medicare-participating MFT increased from 2.5% to 26.5%, and from 27.2% to 55.8% for MHCs. However, only 7.4% of noncore counties had at least one Medicare-participating MFT in October 2024, and 32.2% had at least one MHC.
Medicare participation among MFTs and MHCs increased dramatically following the 2024 coverage expansion, especially among rural providers. However, absolute provider availability in rural counties remains low, underscoring the need for additional strategies to translate participation gains into meaningful improvements in rural mental health access.Mental HealthAccessPolicyAdvocacy -
Digital-Media Use and Mental Health in Children and Adolescents.3 weeks agoDigital media have become a central part of children's and adolescents' daily lives, with increasing usage time and decreasing age of first exposure in recent years. While digital technologies offer opportunities for social participation, access to information, education, and therapeutic support, they are also associated with several risks to mental health. These include problematic use patterns, cyberbullying, exposure to harmful content and hazardous contacts as well as commercial exploitation through manipulative design practices ("dark patterns"). This evidence review summarizes current research on the opportunities and risks of digital media use from a developmental perspective across three age groups (0 - 5, 6 - 13, and 14 - 18 years). Evidence suggests associations between intensive media use and risks for sleep, attention, language development, psychosocial well-being, and academic performance. In adolescence, problematic internet use is also associated with behavioral addictions and mental health problems. Overall, the findings highlight the need for a balanced approach to digital media use, including age-appropriate protection, media literacy, and regulatory measures to safeguard the mental health of young people. This overview forms the basis for the position statement of the German Scientific Society and Associations for Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy on digital media use and mental health of children and adolescents.Mental HealthAccessCare/Management
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Recall bias affects pain and depression assessment in multimorbidity: a pilot study.3 weeks agoOlder adults with multimorbidity (OAMM) commonly receive depression and pain management through primary care, where symptoms are typically assessed through retrospective recall. Even with validated questionnaires, recall bias has been reported in younger populations for both depression and pain. However, recall bias for depression and pain has not been explored in OAMM. We examined discrepancies between prospectively measured and recalled symptoms of depression and pain among OAMM.
We analysed data generated from a 14-day pilot feasibility trial of ecological momentary assessment (EMA) in OAMM (N = 18, age range 67-95). We examined discrepancies between retrospectively assessed depression and pain intensity over two weeks compared to follow-up, baseline characteristics correlated with discrepancies, and recency effects.
We found overreporting across most symptoms, with the largest discrepancies between prospectively recorded and recalled symptom scores for pain intensity and fatigue (d = .49). There was no association between recalled and EMA-measured items for appetite and trouble sleeping. Pain intensity at day 14 was associated with discrepancies in recalled pain (r = -.52, p =.029), and both day 14 mood and negative self-thoughts were associated with discrepancies in trouble concentrating recall (r = -.67, p =.002 and p = -.72, p <.001, respectively) - suggesting recency effects.
We found preliminary evidence of recall bias among OAMM, including overreporting and recency effects of pain and depression symptoms. Given the reliance on recall during primary care visits, more research is needed.Mental HealthAccessAdvocacy -
[Clinical capacity issues in adult eating disorder care in the Netherlands].3 weeks agoClinical care for adults with eating disorders in the Netherlands is under pressure due to limited capacity and long waiting times. Insight into bed capacity, occupancy, and waiting lists in specialized clinics and medical-psychiatric units (MPUs) is lacking.
To gain insight into clinical capacity in eating disorder care in the Netherlands METHOD: A nationwide telephone survey was conducted among 8 clinics and 31 MPUs. Data on capacity, occupancy, waiting lists, and admission criteria were collected between August 26 and September 9, 2025.
The clinics had 115 beds, with 103 occupied and 103 patients waiting. Length of stay ranged from months to longer. Some applied BMI thresholds: compulsory care was limited. MPUs had 40-45 beds, 25 occupied, and 20 waiting. Care ranged from acute somatic interventions to structured weight restoration and compulsory care.
Severe capacity problems, long waiting times, varying admission criteria, and limited compulsory care highlight the urgent need for expansion of capacity, national coordination and stronger collaboration.Mental HealthAccessCare/Management -
[Recovery-oriented thinking reflected in intake reports].3 weeks agoTo emphasize recovery from the very start of treatment, the recovery-oriented intake (ROI) was developed in Dutch mental health care. This approach places additional focus on the personal domain, alongside the usual attention to biological, psychological, and social factors. The question is whether this translates into intake documentation.
To compare ROI with intake as usual (IAU) regarding attention to abovementioned domains of mental health, the degree of integration into a case formulation, and the quality and focus of treatment goals.
In a retrospective file study, 60 intake reports (30 ROI, 30 IAU) were assessed using validated scales for level of detail per domain, integration of information, and quality of treatment goals.
ROI and IAU reports contained a similar level of detail for biological, psychological, and social domains. The personal domain appeared more often in ROI, though usually in isolation. Contrary to expectations, integration was rated higher in ROI. The quality of treatment goals did not differ significantly, but ROI goals more often addressed personal growth and symptoms (26,7% vs 6,7%), whereas IAU goals were more often limited to symptoms (36,7% vs 16,7%).
ROI provides more attention to the personal domain and shows greater integration, without reducing attention to other domains. Strengths are often mentioned in isolation, and social goals remain limited.Mental HealthAccessAdvocacy -
Psychological characteristic subtypes in adolescents with mental disorders and their associations with self-injury behavior and childhood maltreatment.3 weeks agoSelf-injury behavior is a prevalent mental health problem among adolescents. Childhood maltreatment is closely associated with the development of alexithymia, impulsivity, and self-injury behavior in adolescents and young adults with mental disorders; however, the underlying mechanisms remain unclear. This study aims to classify psychiatric patients aged 12 to 24 years into psychological subtypes based on alexithymic and impulsive traits, to explore differences in self-injury behavior among these subtypes, and to examine whether different forms of childhood maltreatment are associated with specific psychological subtypes, thereby providing evidence for clinical intervention and prognosis improvement.
Clinical data of adolescents and young adults with mental disorders treated between 2021 and 2022 were retrospectively collected. Principal component analysis (PCA) was performed using 6 dimensions derived from the Toronto Alexithymia Scale (TAS)-20 and the Barratt Impulsiveness Scale (BIS)-11, including difficulty identifying feelings (DIF), difficulty describing feelings (DDF), externally oriented thinking (EOT), attentional impulsiveness, motor impulsivity, and non-planning impulsivity. Principal components with eigenvalues (λ) ≥1 were retained, and their scores were subjected to 2-step cluster analysis for automatic subtype classification. Differences among the subtypes were compared with respect to demographic characteristics, clinical features, and self-injury behavior-related characteristics. Multivariate Logistic regression models were subsequently used to examine associations between the identified psychological subtypes and different forms of childhood maltreatment.
A total of 634 adolescents and young adults with mental disorders were included, among whom 459 (72.4%) had a history of self-injury behavior. The diagnostic distribution comprised depressive disorders (n=295, 46.5%), bipolar disorder (n=136, 21.5%), anxiety disorders (n=61, 9.6%), schizophrenia (n=14, 2.2%), and other disorders (n=128, 20.2%), including personality disorders, obsessive-compulsive disorder, post-traumatic stress disorder, somatoform disorders, and eating disorders. PCA reduced the 6 dimensions related to alexithymia and impulsivity into 2 independent principal components (Z1 and Z2). Based on individual scores on Z1 and Z2, 2-step cluster analysis automatically classified participants into 3 clusters (K1, K2, and K3). The psychological characteristics of the K1 group were characterized by high motor impulsivity accompanied by marked difficulties in identifying and expressing emotions. The K2 group exhibited relatively low levels of impulsivity and alexithymia. The K3 group was characterized by high attentional impulsivity, high non-planning impulsivity, and externally oriented thinking. No significant differences were observed among the 3 groups in the distribution of primary psychiatric diagnoses (P>0.05). Comparisons of self-injury behavior-related characteristics showed that the K2 group had significantly lower rates of self-injury, lower self-injury frequency, lower self-injury addiction scores, and lower self-injury motivation scores than the other 2 groups (all P<0.05). No significant differences were found between the K1 and K3 groups in self-injury prevalence, self-injury addiction scores, and external emotion regulation motives (P>0.05). However, the K1 group scored significantly higher than the K3 group on the motivational dimensions of social influence, internal emotion regulation, and sensation seeking, while exhibiting a lower frequency of self-injury behavior (P<0.05) in the last year. Multivariable Logistic regression analysis revealed that childhood emotional abuse may be a risk factor for developing the K1 psychological subtype; childhood physical abuse may be a risk factor for developing both K1 and K3 psychological subtypes; and childhood emotional neglect was associated with the development of K1 and K2 psychological subtypes.
Adolescents and young adults with mental disorders can be classified into 3 distinct psychological subtypes based on alexithymia and impulsive traits. These subtypes differ in the prevalence and motivational characteristics of self-injury behavior, independent of clinical diagnosis. Furthermore, the development of different psychological subtypes may be associated with exposure to different forms of childhood maltreatment. These findings suggest that providing targeted emotional regulation and impulse-control interventions for adolescents exposed to specific childhood adversities may help reduce the occurrence and frequency of self-injury behavior.Mental HealthAccessCare/ManagementPolicyAdvocacy -
[Comparison of the clinical efficacy of continuous radiofrequency and pulsed radiofrequency in the treatment of elderly patients with thoracic postherpetic neuralgia].3 weeks agoPostherpetic neuralgia (PHN) is a common long-term complication of herpes zoster infection and severely impairs patients' quality of life. This study aims to compare the clinical efficacy of continuous radiofrequency (CRF) and pulsed radiofrequency (PRF) in the treatment of elderly patients with PHN.
A total of 181 elderly inpatients with PHN who underwent CRF (CRF group, n=101) or PRF (PRF group, n=80) treatment targeting the dorsal root ganglion (DRG) of the thoracic spinal nerve at the Department of Pain Medicine, First Affiliated Hospital of Xi'an Jiaotong University, between March 2020 and March 2022 were enrolled. Patients were followed up at 1 week, 1 month, 3 months, 6 months, and 12 months after treatment. Pain intensity was assessed using the Visual Analogue Scale (VAS), sleep quality using the Athens Insomnia Scale (AIS), anxiety using the Generalized Anxiety Disorder 7-item scale (GAD-7), and depression using the Patient Health Questionnaire-9 (PHQ-9). The incidence of complications and the rate of pain recurrence were also recorded and compared between the 2 groups.
At all follow-up time points after treatment, VAS, AIS, GAD-7, and PHQ-9 scores in both groups were significantly lower than those before treatment (all P<0.001). At 1 week postoperatively, there were no significant differences between the 2 groups in any of these scores (all P>0.05). However, at 1, 3, 6, and 12 months after treatment, VAS scores in the CRF group were significantly lower than those in the PRF group (all P<0.001). In addition, AIS, GAD-7, and PHQ-9 scores were also significantly lower in the CRF group than in the PRF group (all P<0.05). The incidence of postoperative localized numbness was higher in the CRF group than in the PRF group (P<0.05), whereas the 1-year pain recurrence rate was significantly lower in the CRF group (P<0.05).
Both CRF and PRF effectively alleviate pain and improve sleep quality, anxiety, and depressive symptoms in elderly patients with PHN; however, CRF demonstrates superior long-term efficacy compared to PRF.Mental HealthAccessCare/ManagementAdvocacy